The US neutrino community gathered at the Workshop on the Intermediate Neutrino Program at Brookhaven National Laboratory February 4-6, 2015 to explore opportunities in neutrino physics over the next five to ten years. Scientists from particle, astroparticle and nuclear physics participated in the workshop. The workshop examined promising opportunities for neutrino physics in the intermediate term, including possible new small to mid-scale experiments, US contributions to large experiments, upgrades to existing experiments, R&D plans and theory. The workshop was organized into (...) two sets of parallel working group sessions, divided by physics topics and technology. Physics working groups covered topics on Sterile Neutrinos, Neutrino Mixing, Neutrino Interactions, Neutrino Properties and Astrophysical Neutrinos. Technology sessions were organized into Theory, Short-Baseline Accelerator Neutrinos, Reactor Neutrinos, Detector R&D and Source, Cyclotron and Meson Decay at Rest sessions.This report summarizes discussion and conclusions from the workshop. (shrink)

This paper discusses the debate over whether emotional expressions are spontaneous or intentional actions. We describe a variety of empirical evidence supporting these two possibilities. But we argue that the spontaneous-intentional distinction fails to explain the psychological dynamics of emotional expressions. We claim that a complex systems perspective on intentions, as self-organized critical states, may yield a unified view of emotional expressions as a consequence of situated action. This account simultaneously acknowledges the embodied status of environment, evolution, culture and mind (...) in theories of emotion. (shrink)

© 2016 Regents of the University of California.The Review summarizes much of particle physics and cosmology. Using data from previous editions, plus 3,062 new measurements from 721 papers, we list, evaluate, and average measured properties of gauge bosons and the recently discovered Higgs boson, leptons, quarks, mesons, and baryons. We summarize searches for hypothetical particles such as supersymmetric particles, heavy bosons, axions, dark photons, etc. All the particle properties and search limits are listed in Summary Tables. We also give numerous (...) tables, figures, formulae, and reviews of topics such as Higgs Boson Physics, Supersymmetry, Grand Unified Theories, Neutrino Mixing, Dark Energy, Dark Matter, Cosmology, Particle Detectors, Colliders, Probability and Statistics. Among the 117 reviews are many that are new or heavily revised, including those on Pentaquarks and Inflation. The complete Review is published online in a journal and on the website of the Particle Data Group. The printed PDG Book contains the Summary Tables and all review articles but no longer includes the detailed tables from the Particle Listings. A Booklet with the Summary Tables and abbreviated versions of some of the review articles is also available. (shrink)

In the recent past, several papers have pointed to the possibility that tumour removal generates a permissive environment in which tumour growth is potentiated. This phenomenon has been coined “perioperative tumour growth” and whilst it represents a departure in terms of our attitude to the surgical process, this concept was first hinted at by Paget1Sir James Paget (1814–1899) was a surgeon and physiologist who is widely held (along with Rudolph Virchow) to be the father of the science of pathology. Paget (...) described Paget's disease of the nipple as well as Paget's disease of bone. himself. Despite this, the time interval immediately before and after cancer surgery (i.e. the perioperative period) remains an underutilised interval during which chemotherapeutic regimens are rarely implemented. Herein, we present a summarised review of the literature that supports the concept that tumour removal may potentiate the growth of residual neoplastic disease. We also outline current knowledge regarding underlying mechanisms and in this manner highlight potential therapeutic entry points. Finally, we emphasise the urgent need for trials of agents that could protect patients against the harmful host–tumour interactions that may occur during the perioperative period. BioEssays 28: 433–437, 2006. © 2006 Wiley Periodicals, Inc. (shrink)

De Neys offers a welcome departure from the dual-process accounts that have dominated theorizing about reasoning. However, we see little justification for retaining the distinction between intuition and deliberation. Instead, reasoning can be treated as a case of multiple-cue decision making. Reasoning phenomena can then be explained by decision-making models that supply the processing details missing from De Neys's framework.

Since 2000, research within positive psychology has exploded, as reflected in dozens of meta-analyses of different interventions and targeted processes, including strength spotting, positive affect, meaning in life, mindfulness, gratitude, hope, and passion. Frequently, researchers treat positive psychology processes of change as distinct from each other and unrelated to processes in clinical psychology. This paper presents a comprehensive framework for positive psychology processes that crosses theoretical orientation, links coherently to clinical psychology and its more dominantly “negative” processes, and supports practitioners (...) in their efforts to personalize positive psychological interventions. We argue that a multi-dimensional and multi-level extended evolutionary approach can organize effective processes of change in psychosocial interventions, by focusing interventions on context-appropriate variation, selection, and retention of processes, arranged in terms of key biopsychosocial dimensions across psychological, biophysiological, and sociocultural levels of analysis. We review widely studied positive psychology constructs and programs and show how this evolutionary approach can readily accommodate them and provide a common language and framework for improving human and community flourishing. We conclude that Interventions should start with the person, not the protocol. (shrink)

Despite the significant contribution of cognitive-behavioral therapy to effective treatment options for specific syndromes, treatment progress has been stagnating, with response rates plateauing over the past several years. This stagnation has led clinical researchers to call for an approach that instead focuses on processes of change and the individual in their particular context. Process-based therapy is a general approach representing a model of models, grounded in evolution science, with an emphasis on idiographic methods, network models of case conceptualization, and enhancing (...) wellbeing. In this paper, we describe the theory underlying PBT and present a case study for how to apply PBT tools and principles to deliver process-informed and person-centered evidence-based treatment. In addition, we discuss lessons learned from our case and provide suggestions for future considerations when implementing PBT in clinical settings. (shrink)

Live donor kidney transplantation is the best treatment option for most patients with late-stage chronic kidney disease; however, the rate of living kidney donation has declined in the United States. A consensus conference was held June 5-6, 2014 to identify best practices and knowledge gaps pertaining to live donor kidney transplantation and living kidney donation. Transplant professionals, patients, and other key stakeholders discussed processes for educating transplant candidates and potential living donors about living kidney donation; efficiencies in the living donor (...) evaluation process; disparities in living donation; and financial and systemic barriers to living donation. We summarize the consensus recommendations for best practices in these educational and clinical domains, future research priorities, and possible public policy initiatives to remove barriers to living kidney donation. (shrink)

This essay questions the way in which continental Western Christians welcome political implementation (i.e., integration into the publicly funded welfare network and collaboration with heterodox Christians, members of other religions, or irreligious humanitarians) when offering their diaconic services. Among the theological assumptions underlying such reliance from outside the Church, this essay takes special issue with the idea that Christianity's “ethical” commitment to charity can be separated from its spiritual (e.g., liturgical, ascetical, missionary) concerns. Such separation suggests prioritizing charity recipients’ needs (...) over against the framing character of charity providers’ Christian love. On the philosophical level, this same separation refashions Christian philanthropy in terms of a secularly construed “human dignity.” This dignity, even though nominally endorsed by the welfare bureaucracy, is however shown to get repudiated by the objectifying and depersonalizing implications of publicly funded social services. On the theological level, the potentially anti-Christian implications of secularly implemented “diakonia” are pointed out. The scriptural bases usually invoked for the prioritizing of needs are exposed as unfit to offer the hoped-for justification. As a result, only, and at most, a very limited, reserved, and watchful material cooperation with the secular state and with those outside the Church is recommended for Christian “diakonia.”. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Experiential Avoidance and Superstition: Considering Concepts in ContextRoger Vilardaga (bio) and Steven C. Hayes (bio)Keywordsacceptance, contextualism, influence, therapyThe target article (García-Montes et al. 2008) explores the application of the concept of superstition, examined from a Sartrian perspective, to psychopathology such as obsessive–compulsive disorder and psychosis. They compare their analysis to two different technical terms taken from current research programs in psychology, which are the notions of Thought–Action Fusion and (...) Experiential Avoidance (EA). We have been asked to respond because our work in Acceptance and Commitment Therapy (ACT; Hayes, Strosahl, and Wilson 1999) and Relational Frame Theory (RFT; Hayes, Barnes-Holmes, and Roche 2001) are part of the foundational work in EA, and thus in this short commentary we comment on the article from the point of view of our research program.The article notes several areas of overlap between the ACT/RFT work on EA and their Sartrian perspective on superstition, such as the holistic and contextualistic nature of the analysis, but also several differences which the authors feel advantage their own view.It is difficult to compare the two lines of work without appreciating their context and purpose. Sartre was not a scientific psychologist; ACT/RFT are part of a specific effort at scientific system building, which we term here “contextual behavioral science” (AKA, post-Skinnerian behavior analysis).Contextual behavioral science is a social enterprise that has as its purpose the development of increasingly organized statements of relations among events that allow actions embedded in their historical and situational context to be predicted and influenced with precision, scope, and depth. “Precision” means that a limited set of analytic constructs apply to any one event; “scope” means that a limited set of constructs are needed to analyze a broad range of events; and “depth” means that constructs should cohere across different levels of analysis.Although a real world (or at least the one world) is assumed, the partitioning of the world is thought to be the result of our continuous interactions in and with it. These partitions are not ontological constructions from the perspective of contextual behavioral science because they, too, are actions that are purposive and embedded in their historical and situational contexts. The [End Page 269] deliberate attempt to analyze the world scientifically does not contradict the holistic standpoint of contextualism. When analytic goals are accomplished, constructs are “true,” but multiple truths are possible given multiple goals and historical and situational contexts. Conversely, all forms of contextualism become dogmatic and self-contradictory if their goals are not stated. It is common for contextualists of all varieties to state and defend the ultimate apprehension of reality as a whole, for example, without realizing that any statement about the world including such a defense is a form of breaking down this whole into parts. As we will try to show, the target article seems to fall into this usual contextualistic trap by arguing for what is better, without stating clearly “better for what, assessed how” and without viewing concepts with relevance to their purpose.Prediction and influence with precision, scope, and depth is a purpose, stated naked and in the wind. It is not defended, justified, or given ontological status. To generate powerful ways of speaking as measured against that purpose, contextual behavioral science has embraced a wide variety of methodologies, including laboratory research designed to refine behavioral principles with high levels of precision and scope, and applied research such as randomized controlled trials, analog research, and measure development that test the scope of the principles and theories that result (e.g., Hayes et al. 2006). Whether concepts like EA are helpful is a matter to be considered relevant to the goals of the analysis.As example of the kind of problems the authors create for themselves, consider the following quote from the target article:Although the post-Skinnerians who proposed the EA concept call themselves “contextualists,” they pay no more than lip service to the role of the “social/verbal community” and the cultural context. Their research focuses almost exclusively on laboratory experiments, and does not consider the important role of particular social practices and contexts, such as modernity.(García... (shrink)

PURPOSE:To report the localization of a gene causing drusen and macular degeneration in a previously undescribed North American family. METHODS:Genetic mapping studies were performed using linkage analysis in a single family with drusen and atrophic macular degeneration. RESULTS:The clinical manifestations in this family ranged from fine macular drusen in asymptomatic middle-aged individuals to atrophic macular lesions in two children and two elderly patients. We mapped the gene to chromosome 6q14 between markers D6S2258 and D6S1644. CONCLUSIONS:In a family with autosomal dominant (...) drusen and atrophic macular degeneration, the gene maps to a 3.2-cM region on chromosome 6q14. This locus appears to be distinct from, but adjacent to, the loci for cone-rod dystrophy 7 (CORD7) and North Carolina macular dystrophy (MCDR1). Future identification of the gene responsible for the disease in this family will provide a better understanding of macular degeneration. (shrink)